MyBioSource.com's BAIAP2 antibody is a Mouse monoclonal antibody. The BAIAP2 antibody was generated using BAIAP2, BAP2, and IRSp53 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Mouse monoclonal BAIAP2 antibody
BAIAP2 has been identified as a brain-specific angiogenesis inhibitor (BAI1) -binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It alsoassociates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibersand cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affectneuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease